Jacob's Cure is a non-profit organization founded by Jordana Holovach to save her son, Jacob, who was diagnosed with Canavan Disease at six months old. Children with Canavan become trapped in their bodies, develop seizures, lose their ability to see and swallow, and die in the first decade of life. The research funded by Jacob's Cure has slowed or halted the progression of the disease in most of the children who received gene-therapy and have begun the recommended pharmacological regimen. While there is currently no cure for Canavan Disease, Jacob's Cure is funding a stem cell trial that aims to further treat and ultimately cure Canavan disease. This stem cell research may very well revolutionize the manner in which "white matter" neurological diseases, such as Parkinson's, MS and ALS, are treated and will be a model for their cure.
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